Publications

PUBLICATIONS: PEER-REVIEWERED PUBLICATIONS

(*Indicates Dr. Lugo as the corresponding author. # indicates Baylor graduate student. indicates Baylor undergraduate student)

Binder, M. S. # & Lugo, J. N. * (In Press). NS-Pten knockout mice show sex- and age-specific differences in ultrasonic vocalizations. Brain and Behavior.

Hodges, S.L. #, Nolan, S.O. #, Taube, J.H., Lugo, J.N. * (In Press). Adult Fmr1 knockout mice present with deficiencies in hippocampal interleukin-6 and tumor necrosis factor-α expression. NeuroReport.

Nolan, S.O. #, Reynolds, C. D., Smith, G. D. #, Holley, A. J. #, Escobar, E., Chandler, M. A., Volquardsen, M., Jefferson, T., Pandian, A., Smith, T., Nolan, S.O. #, Huebschman, J.L., and Lugo, J. N. * (In Press). Deletion of Fmr1 results in sex-specific changes in behavior. Brain and Behavior.

Chernoff, N., Hill D,J., Diggs, D.L., Faison, B.D., Francis, B.M., Lang, J.R., Larue, M.M., Le, T.T., Loftin, K.A., Lugo, J.N., Schmid, J.E., Winnik, W.M. (2017). A critical review of the postulated role of the non-essential amino acid, β-N-methylamino-L-alanine, in neurodegenerative disease in humans. J Toxicol Environ Health B Crit Rev. 2017;20(4):1-47. doi: 10.1080/10937404.2017.1297592.

Reynolds, C. D., Nolan, S.O. #, Huebschman, J.L., Hodges, S.L. #, Lugo, J.N. * (2017). Early-life status epilepticus acutely impacts select quantitative and qualitative features of neonatal vocalization behavior: Spectrographic and temporal characterizations in C57BL/6 mice. Epilepsy Behav. 2017 May 30;72:58-62. doi: 10.1016/j.yebeh.2017.04.025.

Hodges, S. L. #, Nolan, S. O. #, Reynolds, C. D., Lugo, J. N. * (2017). Spectral and temporal properties of calls reveal deficits in ultrasonic vocalizations of adult Fmr1 knockout mice. Behavioral Brain Research. May 26;332:50-58. doi: 10.1016/j.bbr.2017.05.052.

Lugo, J.N. *, Thompson, M. H,, Huber, P., Smith, G. #, Kwon, R.Y. (2017). Neuron subset-specific Pten deletion induces abnormal skeletal activity in mice. Experimental Neurology. May;291:98-105. doi: 10.1016/j.expneurol.2017.02.002.

Smith, G. D. #, Ahmed, N., Arbuckle, E. #, Lugo, J.N. * (2017). Early-life status epilepticus induces long-term deficits in anxiety and spatial learning in mice. International Journal of Epilepsy. http://dx.doi.org/10.1016/j.ijep.2016.12.005.

Reynolds, C.D., Nolan. S.O.#, Jefferson. T., J.N.* (2016). Sex-specific and genotype-specific differences in vocalization development in FMR1 knockout mice. Neuroreport. Dec 14;27(18):1331-1335.

Smith, G.D. #, White, J., & Lugo, J. N.* (2016). Superimposing Status Epilepticus on Neuron Subset-Specific PTEN Haploinsufficient and Wild Type Mice Results in Long-term Changes in Behavior. Scientific Reports.Nov 7;6:36559. doi: 10.1038/srep36559.

Reynolds, C. #, Smith, G. D., Jefferson, T. S. #, Lugo, J. N. * (2016). Early-life seizures produce a sex-specific suppression of ultrasonic vocalizations in neonatal mice. Epilepsia. Sep;57(9):1377-85. doi: 10.1111/epi.13450.

Smith, G. D. #, Gao, N., Lugo, J. N. * (2016). Kv4.2 knockout mice display learning and memory deficits in the Lashley maze. F1000 Research. 5:2456. doi: 10.12688/f1000research.9664.2. eCollection 2016.

Holley, A. J. # & Lugo, J. N*. (2016). Effects of an Acute Seizure on Associative Learning and Memory. Epilepsy and Behavior, Jan;54:51-7.

Reynolds, C., Smith, G. D. #, Jefferson, T. S., Lugo, J. N. * (2015). Comparison of Equivalence Between Two Commercially Available S499-phosphorylated FMRP Antibodies in Mice. PLOS One. Nov 18;10(11):e0143134. doi: 10.1371/journal.pone.0143134.

Arbuckle, E. P., Smith, G., Gomez, M., Lugo, J. N. (2015). Testing for Odor Discrimination and Habituation in Mice. Journal of Visualized Experiments. May 5(99) e52615.

Elston, T. W., Pandian, A., Smith, G. D., Holley, A. J., Gao, N., Lugo J. N. (2014). Aniracetam Does Not Alter Cognitive and Affective Behavior in Adult C57BL/6J Mice. PLoS One. Aug 6;9(8):e104443. doi: 10.1371/journal.pone.0104443. eCollection 2014.

Lugo, J. N., Smith, G. D., Arbuckle, E. P., White, J., Holley A, J., Floruta, C. M., Ahmed, N., Gomez, M. C., Okonkwo, O. (2014). Deletion of PTEN produces autism-like behavioral deficits and alterations in synaptic proteins. Front Mol Neurosci. Apr 16;7:27. doi: 10.3389/fnmol.2014.00027. eCollection 2014.

Lugo, J. N., Smith, G., Holley, A. (2014). Trace fear conditioning in mice. Journal of Visualized Experiments. Mar 20;(85). doi: 10.3791/51180.

Lugo, J.N., Swann, J.W, Anderson A.E.(2014). Early-life seizures result in deficits in social behavior and learning. Exp Neurol. Jun;256:74-80. doi: 10.1016/j.expneurol.2014.03.014.

Lugo, J. N., Smith, G. D., Morrison, J. B., White, J. (2013). Deletion of PTEN produces deficits in conditioned fear and increases fragile X mental retardation protein. Learning and Memory. Nov 15;20(12):670-3. doi: 10.1101/lm.032839.113.

Brewster, A. L., Lugo, J. N., Patil, V. V., Lee, W. L., Qian, Y., Vanegas, F., Anderson, A. E. (2013). Rapamycin reverses status epilepticus-induced memory deficits and dendritic damage. PLOS ONE. 8(3):e57808. PMID: 23536771

Marcelin, B., Lugo, J.N., Brewster, A. L., Liu, Z., Lewis, A. S., McClelland, S., Chetkovich, D. M., Baram, T. Z., Anderson, A. E., Becker, A., Esclapez, M., Bernard C. (2012). Differential dorso-ventral distributions of Kv4.2 and hyperpolarization-activated cyclic adenosine monophosphate gated channel (HCN) proteins confer distinct integrative properties to hippocampal CA1 pyramidal cell distal dendrites. Journal of Biological Chemistry. May 18;287(21):17656-61. PMID:22511771

Lugo, J. N., Brewster, A. L., Spencer, C.M., Anderson, A. E. (2012). Kv4.2 knockout mice show hippocampal-dependent learning and memory deficits. Learning and Memory, Apr 13;19(5):182-9

Sunnen, C.N., Brewster, A. L., Lugo, J. N., Venegas, F., Turcios, E., Mukhi, S., Parghi, D., D’Arcangelo, D., Anderson, A. E. (2011). Inhibition of the mammalian target of rapamycin blocks epilepsy progression in NS-PTEN conditioninal knockout mice. Epilepsia, Nov;52(11): 2065-75. PMID: 22505720

Ljungberg, C., Sunnen, C.N., Lugo, J. N., Anderson, A. E. & D’Arcangelo, G. D. (2009). Rapamycin suppresses seizures and neuronal hypertrophy in a mouse model of cortical dysplasia. Disease Models & Mechanisms. Jul-Aug;2(7-8): 389-398. PMCID: PMC2707106.

Barnwell, L. F. S., Lugo, J. N., Lee, W., Willis, S. E., Gertz, S. J., Hrachovy, R. A., Anderson, A. E., (2009). Kv4.2 knockout mice demonstrate increased susceptibility to convulsant stimulation. Epilepsia. Jul; 50(7): 1741-1751. PMCID: PMC2925051.

Lugo, J. N., Barnwell, L. F., Johnston, L. D., Kim, R., Feng, C., Hrachovy, R. A., Sweatt, J. D., & Anderson, A. E. (2008). Altered phosphorylation and localization of the A-type channel, Kv4.2 in status epilepticus. Journal of Neurochemistry. Aug;106(4): 1929-40. PMCID2678944.

Jung, S., Jones, T. D., Lugo, J. N., Sherrin, A. H., Sherrin, J. W., D’Ambrosio, R., Anderson, A. E., Poolos, N. P. (2007). Progressive Dendritic HCN Channelopathy during Epileptogenesis in the Rat Pilocarpine Model of Epilepsy. Journal of Neuroscience. 27(47), 13012-12021. PMID: 18513371.

Gass, G. T., Jenkins, W. J., Marino, M. D., Lugo Jr., J. N., Kelly, S.J. (2007). Alcohol exposure during development: Analysis of effects on female sexual behavior. Alcoholism: Clinical and Experimental Research. 31(12), 2065-2072. PMID: 17949467.

Lugo Jr., J. N., Wilson, M. A., Kelly, S. J. (2006). Perinatal ethanol exposure alters met-enkephalin levels of male and female rats. Neurotoxicology & Teratology, 28(2), 238-244. PMID: 16457985.

Lugo Jr., J. N., Marino, M. D. Gass, J. T., Wilson, M. A., & Kelly, S. J. (2006). Alcohol exposure during development reduces resident aggression and testosterone in rats. Physiology & Behavior, 87(2), 330-337. PMID: 12724179.

Lugo Jr., J. N., Marino, M D., Cronise, K., Kelly, S. J. (2003). Effects of alcohol exposure during development on social behavior in rats. Physiology and Behavior, 78(2), 185-194. PMID: 12576115.

Marino, M., Cronise, K., Lugo, J. N., & Kelly, S. J. (2002). Ultrasonic Vocalizations and Maternal-Infant Interactions in a Rat Model of Fetal Alcohol Syndrome. Developmental Psychobiology, 41(4), 341-351. PMID: 12430158.

PUBLICATIONS: OTHER

Lugo, J. N., Lee, W., & Anderson, A. E. (2009). Epilepsy genes- A. Single gene mutations as a cause of epilepsy: Post-translational modification of ion channels in epilepsy. In P. A. Schwartzkroin (Ed.), Encyclopedia of Basic Epilepsy Research. Oxford, UK: Elsevier Ltd., 658-662.

Wilson, M. A., Burghardt, P. R., Lugo Jr., J. N., Primeaux, S. D., Wilson, S. P. (2003). Effect of amygdalar opioids on the anxiolytic properties of ethanol. Annals of the New York Academy of Sciences (986): The Amygdala in Brain Function: Basic and Clinical Approach., 472-475. PMID: 12724179.